Spike-frequency adaptation: phenomenological model and experimental tests


Spike-frequency adaptation is a common feature of neural dynamics. Here we present a low-dimensional phenomenological model whose parameters can be easily determined from experimental data. We test the model on intracellular recordings from auditory receptor neurons of locusts and demonstrate that the temporal variation of discharge rate is predicted with high accuracy. We relate the model to biophysical descriptions of adaptation in conductance-based models and analyze its implications for neural computation.

Matthias Bethge
Matthias Bethge
Professor for Computational Neuroscience and Machine Learning & Director of the Tübingen AI Center

Matthias Bethge is Professor for Computational Neuroscience and Machine Learning at the University of Tübingen and director of the Tübingen AI Center, a joint center between Tübingen University and MPI for Intelligent Systems that is part of the German AI strategy.